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Esketamine's Therapeutic Effect on Anhedonia: A Post-hoc of a Randomized Controlled Trial

Research Square July 20, 2026 preprint DOI: 10.21203/rs.3.rs-10020524/v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial, post-hoc analysis
Population Patients with treatment-resistant depression
Intervention Esketamine
Topics Esketamine
Key findings Esketamine reduced anhedonia symptoms compared to placebo in patients with treatment-resistant depression.

Abstract

Esketamine's Therapeutic Effect on Anhedonia: A Post-hoc of a Randomized Controlled Trial