Ketamine-like effects after recreational use of methoxetamine.
Katharina E Hofer, Bettina Grager, Daniel Müller, Christine Rauber-Lüthy, Hugo Kupferschmidt, Katharina Rentsch, Alessandro Ceschi
Annals of emergency medicine July 1, 2012 DOI: 10.1016/j.annemergmed.2011.11.018 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 19-year-old man |
| Intervention | symptomatic treatment |
| Topics | Esketamine Ketamine |
| Key findings | Methoxetamine produces ketamine-like effects and complete recovery can be expected with supportive care. |
Abstract
Methoxetamine, the N-ethyl derivative of ketamine, is a novel recreational drug that is not at present subject to restrictive regulations in most countries. To our knowledge, no case of methoxetamine abuse has been published to date in the scientific literature, and the only sources of information are illegal drug users' Web discussion forums. We report the first case of analytically confirmed intravenous methoxetamine abuse in a 19-year-old man. Observed signs and symptoms such as tachycardia, hypertension, confusion, agitation, stupor, ataxia, mydriasis, and nystagmus were consistent with ketamine-induced adverse effects and resolved with symptomatic treatment. According to this case report, user Web reports, and the chemical structure, methoxetamine produces ketamine-like effects. Complete recovery can be expected with supportive care.
Comparable studies
Other case reports and case series on ketamine, most cited first.
Citations in the library
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- From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis 2014
- Legal highs: staying on top of the flood of novel psychoactive substances Therapeutic Advances in Psychopharmacology January 26, 2015
- The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor. PLoS One June 14, 2016
- From “Special K” to “Special M”: The Evolution of the Recreational Use of Ketamine and Methoxetamine CNS Neuroscience & Therapeutics June 1, 2013
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