Association between decentering and reductions in relapse/recurrence in mindfulness-based cognitive therapy for depression in adults: A randomized controlled trial.
Michael Moore, Mark A. Lau, Emily A. P. Haigh, Brandilyn R. Willett, Colin M. Bosma, David M. Fresco
Journal of Consulting and Clinical Psychology February 1, 2022 DOI: 10.1037/ccp0000718 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 227 |
| Population | Formerly depressed individuals |
| Interventions | Mindfulness-based cognitive therapy relaxation group therapy treatment as usual |
| Duration | Acute treatment phase (pre- to posttreatment); relapse assessed at 3, 6, 9, and 12 months posttreatment |
| Topics | Meditation Depression |
| Keywords | Mindfulness-based cognitive therapy Psycinfo Depression economics Randomized controlled trial Clinical psychology Psychotherapist Relapse prevention Feeling Psychological intervention Brief psychotherapy Cognition Medline |
| Citations | 33 |
| Key findings | Gains in decentering from mid- to posttreatment predicted reductions in depression and lower relapse rates, but this effect was not specific to MBCT. |
Abstract
Objective: "Decentering" is defined as the ability to observe one's thoughts and feelings as temporary, objective events in the mind (Safran & Segal, 1990), and is increasingly regarded as a candidate mechanism in mindfulness-based interventions. The present study sought to examine the role of decentering, and other related variables, in the efficacy of Mindfulness-based cognitive therapy (MBCT) as compared to two active comparison conditions.
Method: Formerly depressed individuals (N = 227), randomly assigned to MBCT (n = 74), relaxation group therapy (RGT; n = 77) or Treatment as usual (TAU; n = 76), completed self-report measures of decentering and symptoms of depression at pre-, mid-, and posttreatment, and relapse was assessed at 3, 6, 9, and 12 months, posttreatment.
Results: With regard to the acute treatment phase, results indicated that, whereas levels of depression increased in both RGT and TAU, MBCT patients remained free from symptom gains. Moreover, gains in decentering from mid- to posttreatment predicted reductions in depression from pre- to posttreatment for MBCT and TAU, but not for RGT. Participants who experienced increases in decentering, measured from mid- to posttreatment, generally evidenced the lowest levels of relapse/recurrence (during the four follow-up assessments), largely irrespective of treatment group. However, results related to change in decentering should be considered exploratory due to small cell sizes among participants who did not experience gains in decentering.
Conclusions: Taken together, these results suggest that decentering is a potent mechanism for reduction of relapse in major depression, albeit one that is nonspecific to MBCT. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
Comparable studies
Other randomized controlled trials on depression, most cited first.
Citations in the library
Cited by 13
- Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being. Journal of Clinical Medicine March 3, 2025
- The Correlation Between Mindfulness, Decentering, and Psychological Problems: A Structural Equation Modeling Meta-Analysis Mindfulness July 2, 2024
- Be more mindful: Targeting addictive responses by integrating mindfulness with cognitive bias modification or cue exposure interventions Neuroscience & Biobehavioral Reviews September 25, 2023
- Cognitive Behavioral Therapy and Mindfulness-Based Cognitive Therapy for Depressive Disorders: Enhancing Access and Tailoring Interventions in Diverse Settings. Advances in experimental medicine and biology 2024
- Shedding Light on Changes in Subjective Experience During an Intensive Contemplative Retreat: The Lyon Assessment of Meditation Phenomenology Questionnaire. Biological Psychiatry Global Open Science July 1, 2025
and 8 more in the library