Pre-existing brain function predicts subsequent practice of mindfulness and compassion meditation.
Jennifer S Mascaro, James K. Rilling, Lobsang Tenzin Negi, Charles L. Raison
Neuroimage April 1, 2013 DOI: 10.1016/j.neuroimage.2012.12.021 (opens in new tab) via PubMed
Summary
AI-generated from the abstractActivity in brain regions linked to empathy, such as the anterior insula, before training predicted how much time people later spent practicing compassion meditation, while activity in the amygdala, a region involved in threat processing, predicted less time practicing mindfulness meditation. After training, there was no difference in brain responses between the compassion meditation group and an active health education control group. The findings suggest that pre-existing neurobiological profiles may influence how readily individuals engage with different meditation techniques.
Study at a glance
| Characteristics | Observational cohort with an active control group Peer reviewed |
|---|---|
| Sample size | 21 |
| Population | Adults who completed meditation training |
| Interventions | Compassion meditation Health education |
| Key finding | Baseline activation of the anterior insula in response to others' pain predicted greater engagement with compassion meditation, while baseline left amygdala activity in response to one's own pain predicted less engagement with mindfulness meditation. |
Abstract
While a variety of meditation techniques are increasingly employed as health interventions, the fact that meditation requires a significant commitment of time and effort may limit its potential widespread utility. In the current study, we ask whether baseline subjective reports or brain activity in response to a "Pain for Self and Others" paradigm predicts subsequent engagement in mindfulness and compassion meditation. The study also investigated whether compassion training would impact neural responses when compared to an active health education control group. Prior to training, activation of the left and right anterior insula, an area thought to be important for empathy, in response to the Other pain task was positively related to engagement with compassion meditation as measured by practice time (n=13). On the other hand, activity in the left amygdala during the Self pain task was negatively correlated with mindfulness practice time. Following the study intervention, there was no difference between the compassion group (n=13), and the control group (n=8), in brain responses to either the Self or Other task. These results are the first to indicate that baseline neural responses may predict engagement with meditation training and suggest that pre-existing neurobiological profiles differentially predispose individuals to engage with disparate meditation techniques.