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Effectiveness of mindfulness-based cognitive therapy on the management of depressive disorder: Systematic review

Zulkiflu Argungu Musa, Soh Kim Lam, Firdaus Binti Mamat @ Mukhtar, Soh Kwong Yan, Oladele Tajudeen Olalekan, Soh Kim Geok

International Journal of Africa Nursing Sciences May 1, 2020 DOI: 10.1016/j.ijans.2020.100200 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Peer reviewed
Sample size 15
Population People with depressive disorders
Intervention Mindfulness-Based Cognitive Therapy
Topics Depression Meditation
Keywords Mindfulness-based cognitive therapy
Key findings MBCT leads to a decrease in depressive symptoms, reduction in depression relapse rate, and improvement in mindfulness.

Abstract

Mindfulness-Based Cognitive Therapy (MBCT) was developed to prevent relapse in people with depressive disorders, and it help individuals better understand and manage their thoughts and emotions in order to achieve relief from feelings.

Objective: The objective of this paper is to review and evaluate the effectiveness of MBCT on the management of depression.

Method: To find appropriate studies, the electronic search of the following databases (PsycINFO, PubMed, Medline CINAHL, Ebsco Host, Google scholar, and AJOL) using the keywords mindfulness, depression, depressive disorders and mindfulness-based cognitive therapy between 2009 and 2019 was done. Studies that showed empirical evidence, were an experimental study (randomized and non-randomized) and whose full text was available were evaluated.

Result: Fifteen articles were identified, out of fifteen, fourteen were randomized while one study was a non-randomized study. Based on the analysis, the most solid outcomes for all published articles were that MBCT leads to a decrease in depressive symptoms, reduction in depression relapse rate and improvement in terms of mindfulness.

Conclusion: There was a piece of great evidence that MBCT has a better outcome, the MBCT presented as a promising addition for the management of depression. Researchers need to shape inadequate time points in the study designs so as to be able to regulate the form and temporal sequencing of change. Finally, findings from this systematic review can be used by nurses and other mental health practitioners on the efficacy and patient population which best respond to the MBCT technique.

Comparable studies

Other systematic reviews and meta-analyses on depression, most cited first.

Study Year Design Participants
Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression Participants with major depression in placebo-controlled, double-blind, randomized... 2015 Systematic review and meta-analysis
Side-effects associated with ketamine use in depression: a systematic review. Patients with depression 2018 Systematic review
Comparative efficacy of racemic ketamine and esketamine for depression: a systematic review and meta-analysis Adults with unipolar or bipolar major depression 2020 Systematic review and meta-analysis n = 1,877
Single-dose infusion ketamine and non-ketamine N-methyl-D-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories Patients with major depressive disorder or bipolar depression 2016 Systematic review and meta-analysis n = 588
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188

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