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The correlation between cumulative burden of mental disorders and self-harm, shame, and insight in young female patients with schizophrenia.

Hua Xue, Chaomin Wang, Yongjian Tian, Ziliang Guo, Congmin Zhang, Lin Liu, Cuixia An, Lili Zhang, Suying Niu, Jianghua Cao, Yali Di, Na Li

European Archives of Psychiatry and Clinical Neuroscience April 1, 2025 DOI: 10.1007/s00406-024-01860-6 (opens in new tab) via PubMed

Summary

AI-generated from the abstract

An 8-week Mindfulness-Based Cognitive Therapy (MBCT) intervention reduced stigma and self-harm, and improved mindfulness and insight in young women with schizophrenia. In a randomized trial of 62 female patients, those receiving MBCT showed significantly lower scores on measures of stigma and self-harm compared to a control group receiving conventional treatment. Mindfulness scores and treatment attitudes improved significantly. Higher mindfulness was linked to lower stigma. The findings suggest MBCT can lessen the cumulative burden of mental disorders and self-harm in this population.

Study at a glance

Characteristics Randomized controlled trial Peer reviewed
Sample size 62
Population Young female patients with schizophrenia
Intervention Mindfulness-Based Cognitive Therapy (MBCT)
Duration 8-week intervention
Keywords Insight Mental disorders Schizophrenia Self-harm Stigma
Key finding MBCT significantly reduced stigma and self-harm and improved mindfulness and insight in young women with schizophrenia.

Abstract

This study delves into the correlation between the cumulative burden of mental disorders and self-harm, shame, and insight in young female patients with schizophrenia. A prospective randomized controlled study was used to recruit 62 female schizophrenia patients who met the recruitment conditions from January 2022 to December 2023. The participants were randomly divided into an experimental group (31 cases) and a control group (31 cases) using a computer-based random number distribution method. The experimental group underwent an 8-week Mindfulness-Based Cognitive Therapy (MBCT) intervention, while the control group received conventional treatment. Data was collected using the Modified EI-SHS scale, the Link's Stigma Scale (LSS), the Five-factor Mindfulness Scale (FFMQ), and the Self-awareness and Therapeutic Attitude Questionnaire (ITAQ) before and after the intervention. One-way ANOVA and repeated measure ANOVA were used to compare and analyze the two groups of data. The experimental group exhibited a significant reduction in EI-SHS and LSS scores (100.26 ± 11.48 vs. 88.35 ± 10.09, 112.81 ± 12.30 vs. 100.50 ± 13.52, p < 0.01), coupled with significant increase in FFMQ and ITAQ scores (113.77 ± 12.25 vs. 128.31 ± 14.09, 14.03 ± 4.18 vs. 17.30 ± 2.96, p < 0.01). A positive correlation was found between overall stigma scores and mood disorder scores (r = 0.379, P < 0.011). Correlation analysis revealed a negative correlation between mindfulness (self-awareness) and stigma (r = -0.128, P = 0.025). MBCT effectively reduced stigma in young women with schizophrenia and improved coping tendencies, cognitive status, and attitudes toward mental illness, ultimately reducing the cumulative burden of mental disorders and self-harm in these patients. Increased levels of mindfulness correspond to improved cognitive status and a more positive attitude toward treatment for mental illness. It is of great value to promote MBCT in female patients with schizophrenia.

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