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The effects of short video app-guided mindfulness meditation on rumination, self-compassion, psychological flexibility, and depression among individuals experiencing entrepreneurial failure.

Ye-Hui Tu, Chao Liu, Zheng-Hao Gao, Hao Chen

Frontiers in Psychiatry 2025 DOI: 10.3389/fpsyt.2025.1706661 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 100
Population Recently failed entrepreneurs aged 25-55
Intervention Mindfulness meditation
Dose 3-minute daily sessions
Duration 5-week intervention
Measures Self-Compassion Scale - Short Form (SCS-SF), Acceptance and Action Questionnaire-II (AAQ-II)
Topics Depression Meditation
Keywords Mindfulness meditation Psychological flexibility Rumination Self-compassion
Key findings A five-week app-guided mindfulness intervention significantly reduced rumination and depression and improved self-compassion and psychological flexibility in failed entrepreneurs compared to a waitlist control.

Abstract

This study aimed to evaluate the effectiveness of a short video app-guided mindfulness meditation intervention in improving psychological flexibility and self-compassion and reducing rumination and depressive symptoms among failed entrepreneurs. A randomized controlled trial was conducted with 100 recently failed entrepreneurs (aged 25-55), who were randomly assigned to either an intervention group (n = 50) or a waitlist control group (n = 50). Over five weeks, the intervention group completed daily 3-minute guided mindfulness meditation sessions via a secure mobile app. Psychological outcomes-including rumination, self-compassion, psychological flexibility, and depression-were assessed at pre- and post-intervention using validated instruments(Self-Compassion Scale - Short Form, SCS-SF), psychological flexibility (Acceptance and Action Questionnaire-II, AAQ-II). Data were analyzed using a two-step approach: a 2 (Group: Intervention vs. Control) × 2 (Time: Pre vs. Post) mixed-design MANOVA was first conducted to assess overall multivariate effects, followed by repeated measures ANOVAs for each outcome variable. Significant group × time interaction effects were observed across all outcome variables. Compared to the control group, the intervention group showed significant reductions in rumination (F (1, 98) = 14.485, p <.001, η² = .073) and depression (F(1, 98) = 9.241, p = .003, η² = .045), as well as significant improvements in self-compassion (F(1, 98) = 11.764, p <.001, η² = .057) and psychological flexibility (F(1, 98) = 13.464, p <.001, η² = .064). This study provides robust empirical support for the efficacy of mobile-guided mindfulness interventions in promoting mental health recovery among failed entrepreneurs. The findings highlight the potential of short video-based mindfulness practices as scalable, low-barrier tools to reduce cognitive vulnerability and emotional distress following entrepreneurial failure. Chinese Clinical Trial Registry (ChiCTR), identifier ChiCTR2500106524.

Comparable studies

Other randomized controlled trials on depression, most cited first.

Study Year Design Participants
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression Subjects with DSM-IV major depression (treatment resistant) 2006 Randomized, placebo-controlled, double-blind crossover study n = 18
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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