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The Orientation on Being Program: A Prospective Pilot Study Comparing Its Results With the Standard Mindfulness-Based Stress Reduction Program.

Cees Hoefnagels, Ivan Nyklíček

Psychological Reports July 20, 2026 DOI: 10.1177/00332941261463476 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Quasi-experimental prospective study Randomized Pilot study Peer reviewed
Sample size 81
Population OB program participants (N = 27) and matched MBSR participants (N = 54) in the Netherlands
Intervention Orientation on Being (OB) program
Duration 12-month period, with assessments at 2 months and 12 months
Topics Meditation
Keywords Psychological well-being Quasi-experiment Self-compassion Holistic intervention
Key findings The Orientation on Being program was associated with significant improvements across 12 months in psychological well-being, self-esteem, self-compassion, introspective insight, and mindfulness skills, and decreases in depressive symptoms, anxiety, perceived stress, and rumination, all with large effect sizes. No differences appeared between OB and MBSR at 2 months, but a significant Time × Group interaction indicated the OB group continued to strengthen its gains between 2 and 12 months, which was not evident in the MBSR group.

Abstract

Various programs focus on psychological well-being associated with spiritual and personal growth, but empirical studies assessing the evidence are scarce. The objective of this pilot is to examine the results of the first year of the extensive Orientation on Being (OB) program in the Netherlands. A prospective and quasi-experimental design was used in which changes in various indices of psychological functioning of OB participants (N = 27) were compared with those of matched participants of the standard 8-week Mindfulness-Based Stress Reduction program (MBSR; N = 54) across a 12-month period. Analyses showed that the OB program was associated with significant changes across the 12 months in all but one of the studied outcomes: increased psychological well-being, self-esteem, self-compassion, introspective insight, and mindfulness skills, and decreased depressive symptoms, anxiety, perceived stress and rumination (all with large effect sizes). Differences between the two programs were absent at 2 months, but a significant Time × Group interaction reflected that the OB group further strengthened its beneficial changes between 2 and 12 months, which were not evident in the MBSR group. These results indicate that the OB program was associated with persistent large benefits for psychological functioning. Future studies should employ larger samples in a randomized controlled trial.

Comparable studies

Other experimental studies on meditation, most cited first.

Study Year Design Participants
The benefits of being present: Mindfulness and its role in psychological well-being. Cancer patients (clinical intervention study) 2003 Mixed methods: scale development, correlational, quasi-experimental, laboratory, experience-sampling, and clinical intervention study
Loving-kindness meditation increases social connectedness. 2008 Controlled laboratory experiment
Mindfulness and mind-wandering: Finding convergence through opposing constructs. 2012 Two studies: correlational study and experimental study
Mental Training Enhances Attentional Stability: Neural and Behavioral Evidence 2009 Experimental study
Mindfulness meditation and substance use in an incarcerated population. Incarcerated population 2006 Quasi-experimental with treatment-as-usual control condition

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