Correlation between Activity and Electronic State of Hallucinogenic Amphetamines
Sungzong Kang, Jack Peter Green
Nature May 16, 1970 DOI: 10.1038/226645a0 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or computational analysis Peer reviewed |
|---|---|
| Key points | Argues that hallucinogenic activity correlates with the energy of the highest occupied molecular orbital, based on Hückel calculations on three methoxylated amphetamines, and also notes a correlation with fluorescent properties. |
Abstract
THE actions of hallucinogenic agents have been correlated with Hückel molecular orbital calculations of the π-elections^1 and with fluorescent properties^2. The Hückel correlations on three methoxylated amphetamines indicated that hallucinogenic activity correlated with energy of the highest occupied molecular orbital^1.