Chemistry and Pharmacology of Hallucinogens, Entactogens and Stimulants
Pharmacopsychiatry July 1, 1998 DOI: 10.1055/s-2007-979349 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA Mescaline Psilocybin |
| Keywords | Hallucinogen Tryptamines Amphetamine Pharmacology Designer drug |
| Citations | 32 |
| Key findings | Twenty-eight new amphetamine and tryptamine compounds are calculated to have hallucinogenic effects greater than mescaline. |
Abstract
Amphetamines, tryptamines, phencyclidines, tetrahydrocannabinol and substances of the ecstasy group are characterized as stimulants, hallucinogens and entactogens. The various effects of each group and their mode of action in different transmitter systems are described. 28 new compounds of the amphetamine and tryptamine series has been calculated, which exceed the hallucinogenic effects of mescaline. The different pathways of the metabolism of MDMA (ecstasy) and MDE in humans may probably explain their individual effects.
Comparable studies
Other narrative reviews on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Study of a New Schizophrenomimetic Drug—Sernyl | 1959 | Review | |
| Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways | 2017 | Review | |
| Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine | 2020 | Review | |
| Legal highs: staying on top of the flood of novel psychoactive substances | 2015 | Review | |
| Psychedelic Drugs in Biomedicine | 2017 | Review |
Citations in the library
Cited by 10
- Glutathione and N-Acetylcysteine Conjugates of α-Methyldopamine Produce Serotonergic Neurotoxicity: Possible Role in Methylenedioxyamphetamine-Mediated Neurotoxicity Chemical Research in Toxicology November 19, 1999
- Dark Classics in Chemical Neuroscience: Mescaline ACS Chemical Neuroscience May 30, 2018
- The globalization of traditional medicine in northern peru: from shamanism to molecules. Evidence-based Complementary and Alternative Medicine December 28, 2013
- MDAI (5,6‐methylenedioxy‐2‐aminoindane; 6,7‐dihydro‐5H‐cyclopenta[f][1,3]benzodioxol‐6‐amine; ‘sparkle’; ‘mindy’) toxicity: a brief overview and update Human Psychopharmacology: Clinical and Experimental July 1, 2013
- Síndromes neurológicos asociados con el consumo de plantas y hongos con componente tóxico (II). Hongos y plantas alucinógenos, micotoxinas y hierbas medicinales Revista de Neurología 2003
and 5 more in the library