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Toward a Scientific Model of Meditative Endpoints (MEND). Extremes of Human Experience and Development and the Case of Nirvana

Terje Sparby, Matthew D. Sacchet

November 23, 2025 preprint DOI: 10.31234/osf.io/ta3gn_v1 (opens in new tab)

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Characteristics Theoretical or philosophical paper
Topics Buddhism Meditation
Keywords Enlightenment Focus optics Taxonomy biology Epistemology Point geometry Mental model Cognitive science Mindfulness meditation Perspective graphical
Key points Proposes an integrated taxonomy that differentiates ways of MEND entry, MEND events, and persistent MEND to unify conflicting descriptions of nirvana.

Abstract

Meditation, in particular advanced meditation, develops toward meditative endpoints (MEND), sometimes referred to metaphorically as awakening, enlightenment or salvation. A well-known instance of such an endpoint is called nibbāna (Pali) or nirvana (Sanskrit). Contemporary mindfulness teachers and diverse Buddhist traditions present differing views of nirvana. Some define nirvana as the ultimate reality beyond awareness, while others define it as liberated or pure awareness itself. Some descriptions of nirvana focus on the cessation of various mental phenomena (and particularly the cessation, or end, of suffering) and others based on affirmations (e.g., ultimate happiness). Nirvana has also been defined as ineffable, or as paradoxical (e.g., as neither existence nor non-existence). These, and other, different views and descriptions of nirvana make it challenging to understand this construct, and to establish a science of advanced meditation including meditative endpoints (MEND). Here, we propose an integrated taxonomy that unifies the different views and descriptions. It differentiates between ways of MEND entry, MEND events, and persistent MEND. The proposed taxonomy hence provides a unified view, a framework for differentiating and relating distinct approaches to MEND in the sense of nirvana, and a starting point for investigating MEND beyond the case of nirvana.

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