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Convergence of Cannabis and Psychosis on the Dopamine System

Jessica Ahrens, Sabrina D. Ford, Betsy Schaefer, David Reese, Ali R. Khan, Philip G. Tibbo, Rachel A Rabin, Clifford M. Cassidy, Lena Palaniyappan

JAMA Psychiatry April 9, 2025 DOI: 10.1001/jamapsychiatry.2025.0432 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort Peer reviewed
Topics Cannabis
Key findings Cannabis use is associated with alterations in the midbrain dopamine pathway involved in psychosis.

Abstract

This cohort study investigates the association between cannabis and the midbrain dopamine pathway involved in psychosis.