[Cannabis and psychosis--a review].
Michael P Schaub, Wulf Rössler, Rudolf Stohler
Praxis June 2, 2004 DOI: 10.1024/0369-8394.93.23.997 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Cannabis |
| Key findings | Very high doses of cannabis can induce a brief but rare psychosis, and cannabis use seems to worsen the course of schizophrenia spectrum disorders. |
Abstract
The present review focuses on articles dealing with clinical or epidemiological studies on the association between cannabis use and psychoses. Included are all articles published since 1990 that were located by a Medline or Psyclit data-base research and those earlier articles that are needed for a correct understanding of studies published during the index episode. The three main topics found are 1) is there evidence for a so called cannabis psychosis 2) do cannabis users exhibit a higher risk of developing a psychotic disorder or 3) does its use worsen the course in established schizophrenia spectrum disorders. The review concludes that very high doses of cannabis can induce a brief psychosis but that this condition is extremely rare. Therefore, such a diagnosis should only be made after careful exclusion of other etiologies. The actual evidence regarding the impact of cannabis use on persons vulnerable to psychosis is not conclusive. Cannabis use seems to worsen the course of schizophrenia spectrum disorders. Adolescents run a higher risk from using cannabis than older people. They should be strongly advised not to indulge in such behaviour.
Comparable studies
Other narrative reviews on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Causal association between cannabis and psychosis: examination of the evidence | 2004 | Review | |
| Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history. General (historical and pharmacological review) | 2018 | Review | |
| Psychiatric effects of cannabis | 2001 | Review | |
| Beyond THC: The New Generation of Cannabinoid Designer Drugs | 2011 | Review | |
| Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug | 2006 | Review |
Citations in the library
Cites 8
- Effects of smoking marijuana on brain perfusion and cognition. Neuropsychopharmacology June 2002
- Cannabis use and psychosis: a review of clinical and epidemiological evidence. Australian & New Zealand Journal of Psychiatry February 1, 2000
- Elevated endogenous cannabinoids in schizophrenia. Neuroreport June 3, 1999
- Cannabis psychosis and acute schizophrenia. a case-control study from India. European Addiction Research June 1, 1999
- Cannabis and acute psychosis. Schizophrenia Research September 1, 1994
and 3 more in the library