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The effects of mindfulness‐based interventions on emotion regulation/dysregulation in people with mental health conditions: A systematic review and meta‐analysis

Thomas Easdale‐Cheele, George Nash, Veronika Filobokova, Chloe Westbury, Alessio Bellato

JCPP Advances February 12, 2026 DOI: 10.1002/jcv2.70103 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and meta-analysis Randomized Peer reviewed
Sample size 988
Population People with mental health conditions established by an adequately trained healthcare professional according to DSM or ICD criteria
Topics Meditation
Keywords Mental health Psychological intervention Cognitive reappraisal Cognition Meta-analysis Protocol science Expressive suppression Cognitive appraisal Clinical psychology Quality philosophy
Citations 1
Key findings Mindfulness-based interventions significantly improved cognitive reappraisal and reduced overall emotion dysregulation across diagnoses, but did not significantly affect expressive suppression.

Abstract

Abstract Background We conducted a systematic review and meta‐analysis to examine the effects of mindfulness‐based interventions (MBIs) on emotion regulation (ER) and emotion dysregulation (ED) in people with any mental health condition.

Methods: Following a pre‐registered protocol (PROSPERO CRD42024618605), we searched multiple databases (Web of Science, PsycINFO, Embase, and PubMed) on 04/07/2025. We identified randomised‐controlled trials (RCTs) in which the effects of MBIs on ER or ED were measured in people with mental health conditions established by an adequately trained healthcare professional according to the Diagnostic and Statistical Manual of Mental Disorders (from third to fifth editions) or equivalent diagnosis as per the International Classification of Diseases (ninth or 10th revisions). Pooled effect sizes (Hedge's g ) were estimated using random‐effect meta‐analyses. Study quality was assessed using the Cochrane Risk of Bias Tool 2 .

Results: We identified 19 RCTs, with 16 in the meta‐analyses (988 participants in total; 50.71% randomised to MBIs). We found that MBIs significantly improved cognitive reappraisal ( k = 6, g = 0.65, 95% CI = 0.33, 0.98) and reduced overall ED ( k = 9; g = −0.54; CI = −0.71, −0.36). Significant reductions in ED domains concerning goal‐directedness, impulsivity, and accessing ER strategies were found. Effects for expressive suppression were nonsignificant ( k = 6; g = −0.25; CI = −0.94, 0.45) with significant heterogeneity. Study quality significantly moderated both ER outcomes, though not overall ED.

Conclusion: MBIs show potential for improving cognitive reappraisal and reducing ED across diagnoses. However, limited evidence for younger people and self‐report measurements warrant cautious interpretation.

Trial Registration: NIHR PROSPERO 2024 CRD42024618605. https://www.crd.york.ac.uk/PROSPERO/view/CRD42024618605 .

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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