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"Research chemicals": tryptamine and phenethylamine use among high-risk youth.

Bill Sanders, Stephen E Lankenau, Jennifer Jackson Bloom, Dodi Hathazi

Substance Use & Misuse 2008 DOI: 10.1080/00952990701202970 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative study Pilot study Peer reviewed
Sample size 42
Population High-risk youth recruited in public settings in Los Angeles
Topics Ketamine
Keywords Humans Confusion Hallucinations Substance-related disorders Substance abuse, intravenous Diarrhea Nausea Vomiting Tryptamines Phenethylamines Psychotropic drugs Cross-sectional studies Risk-taking Interview, psychological Health status Adolescent Adult California Female Catchment area, health
Key findings Use of lesser-known tryptamines and phenethylamines among high-risk youth was infrequent, spontaneous, and occurred mainly at music venues, with some purchasing online for private use; short-term negative health outcomes included nausea, vomiting, diarrhea, disorientation, and frightening hallucinations.

Abstract

Tryptamines and phenethylamines are two broad categories of psychoactive substances with a long history of licit and illicit use. Profiles of users of recently emerging tryptamines and phenethylamines are nonexistent, however, since surveillance studies do not query the use of these substances. This manuscript describes the types, modes of administration, onset of use, and context of use of a variety of lesser known tryptamines and phenethylamines among a sample of high-risk youth. Findings are based upon in-depth interviews with 42 youth recruited in public settings in Los Angles during 2005 and 2006 as part of larger study examining health risks associated with injecting ketamine. Youth reported that their use of tryptamines and phenethylamines was infrequent, spontaneous, and predominately occurred at music venues, such as festivals, concerts, or raves. Several purchased a variety of these "research chemicals" from the Internet and used them in private locations. While many described positive experiences, reports of short-term negative health outcomes included nausea, vomiting, diarrhea, disorientations, and frightening hallucinations. These findings, based upon pilot study data, move toward an epidemiology of tryptamine and phenethylamine use among high-risk youth.

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Ketamine for Depression, 4: In What Dose, at What Rate, by What Route, for How Long, and at What Frequency? 2017 Qualitative review
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A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and Depression Healthcare providers 2022 Quality improvement evaluation with mixed methods n = 94
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Expert Opinion on Psychedelic-Assisted Psychotherapy for People with Psychopathological Psychotic Experiences and Psychotic Disorders Experts in psychiatry, clinical psychology, medicine, and psychedelic effects 2024 Qualitative study n = 12

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