PHARMACOLOGICALLY AND TOXICOLOGICALLY RELEVANT COMPONENTS OF Amanita muscaria
J. Patočka, Barbora Kočandrlová
Military Medical Science Letters September 8, 2017 DOI: 10.31482/mmsl.2017.020 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Citations | 14 |
| Key findings | The review summarizes current knowledge on the chemistry, pharmacology, and toxicology of Amanita muscaria, highlighting ibotenic acid and muscimol as the main psychoactive ingredients. |
Abstract
Amanita muscaria, the red fly agaric, is the most famous of all Amanita. The initial history of this fascinating mushroom dates back to at least the 13th century. The use of mushrooms began in antiquity and is associated with mysticism. The collection and consumption of mushrooms and other plants containing psychoactive substances is now very popular, especially among young people who are experimenting with drugs. Ibotenic acid and muscimol are the main active ingredients of this mushroom, but other substances are likely to be involved in the psychotropic effects. A. muscaria also contains some other non-psychotropic substances that are interesting not only for their chemical structure but also for their biological activity. Current knowledge about chemistry, pharmacology and toxicology regarding this fungus is reviewed in this article.