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The Effects of Psychedelic Microdosing on Mental Health: A Systematic Review

David F Lo, Hasan Zia, Adarsh Thakur, Praneetha Rajkumar, Don D. Shamilov

Research Posters May 2, 2024 DOI: 10.31986/issn.2689-0690_rdw.stratford_research_day.96_2024 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Double-blind Peer reviewed
Sample size 16
Population Individuals who microdose psychedelics for mental health conditions
Topics Microdosing
Citations 1
Key findings Microdosing with psychedelics is associated with lower levels of anxiety, depression, and stress, but also with side effects like difficulty sleeping and headaches.

Abstract

This poster explores the effects of psychedelic microdosing on mental health conditions. Roughly 5.5 million individuals in the U.S. utilize psychedelics to treat their mental health issues. The primary substances used for microdosing currently include LSD and psilocybin, but mescaline, DMT, and amphetamines are used less commonly. This systematic review included 16 unique articles. The types of articles included: observational, placebo, self-reported, motivational, literature review, and comparative studies. The studies indicated lower levels of anxiety, depression, and stress among those that microdose. However, drawbacks such as difficulty sleeping and headaches were reported. Various studies have been published on the effects of microdosing, yet studies with greater sample sizes as well as double blind studies would lead to a greater understanding of this modality of treatment.