Successful treatment of intractable MDMA adverse reactions using acupuncture and traditional Chinese medicine
Hope Kronman, Alison Locker, Abdi Assadi, Jeffrey Guss
Journal of Psychedelic Studies April 2, 2025 DOI: 10.1556/2054.2025.00402 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | An individual who suffered from insomnia, anxiety, tinnitus, and more for months following MDMA therapy |
| Intervention | Traditional Chinese Medicine |
| Topics | MDMA |
| Keywords | Acupuncture Adverse effect Alternative medicine Traditional chinese medicine Traditional medicine Pharmacology Plant-based medicinal research |
| Key findings | Symptoms following MDMA therapy that were unresponsive to Western medical management responded to treatment within the Traditional Chinese Medicine framework. |
Abstract
Abstract Psychedelic treatments like MDMA can sometimes have side effects which persist despite management with Western medical approaches. In what follows, we present a case study of an individual who suffered from insomnia, anxiety, tinnitus, and more for months following MDMA therapy. Ultimately, her symptoms responded to management within the Traditional Chinese Medicine framework. We present this case in detail, and argue that psychedelic management, especially in the integration phase, can benefit from the incorporation of techniques which engage with energies that Western medicine do not address.
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cites 34
- MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. Nature Medicine June 1, 2021
- The safety and efficacy of {+/-}3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study. Journal of Psychopharmacology July 19, 2010
- 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a randomised, double-blind, dose-response, phase 2 clinical trial. The Lancet Psychiatry May 1, 2018
- A randomized, controlled pilot study of MDMA (±3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD) Journal of Psychopharmacology October 31, 2012
- MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial. Nature Medicine October 1, 2023
and 29 more in the library