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Detailing a Pilot Study: The "Code of Reality" Protocol, A Phenomenon of N,N-DMT Induced States of Consciousness

Danny Goler

IPI Letters January 8, 2025 DOI: 10.59973/ipil.158 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Pilot study Peer reviewed
Interventions N N-Dimethyltryptamine (N N-DMT)
Topics DMT Philosophy of mind
Key points Individuals under the influence of DMT consistently describe coherent geometric structures and symbols resembling 'code' when observing a diffracted light pattern from a 650 nm laser.

Abstract

This article reports on the discovery of a recurring visual phenomenon observed by individuals under the influence of exogenous N,N- Dimethyltryptamine (N,N- DMT) when observing a diffracted light pattern generated by a collimated 650 nm laser. Using a structured protocol, a pilot study revealed consistent descriptions of coherent geometric structures and symbols resembling "code." This report shares the protocol employed to make this discovery, outlines the experimental setup, and discusses potential implications for understanding altered states of consciousness. The findings offer valuable insights into the neural, psychological, and cognitive mechanisms underlying altered states of consciousness.

Comparable studies

Other non-randomized and open-label trials on DMT, most cited first.

Study Year Design Participants
Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder. Treatment-resistant individuals with major depressive disorder (MDD) and healthy controls 2022 Open-label, fixed-order, dose-escalation exploratory phase 1 study n = 10
A phase 1/2 trial to assess safety and efficacy of a vaporized 5-methoxy-N,N-dimethyltryptamine formulation (GH001) in patients with treatment-resistant depression Adult patients with treatment-resistant depression 2023 Phase 1/2 clinical trial n = 16
Rapid and sustained antidepressant effects of vaporized N,N-dimethyltryptamine: a phase 2a clinical trial in treatment-resistant depression. Patients with treatment-resistant depression 2025 Open-label trial n = 14
Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine. Healthy male subjects 2023 Open-label within-subject study n = 10
Safety and tolerability of inhaled N,N-Dimethyltryptamine (BMND01 candidate): A phase I clinical trial. Healthy volunteers 2024 Open-label, single-ascending, fixed-order, dose-response study n = 27

Citations in the library

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DMT Philosophy of mind Altered states of consciousness