Subjective ibogaine experiences across intersecting social-ecological dimensions
Evan E. Ozmat, Alicia K. Mcdonough, Guy M. Ladouceur, Darin S. Roy, Dana M. Bozek, Jun-Sung Oh, Jessica L. Martin
Journal of Psychedelic Studies May 31, 2024 DOI: 10.1556/2054.2024.00322 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Qualitative study Peer reviewed |
|---|---|
| Sample size | 15 |
| Population | Individuals who received ibogaine treatment at a medical clinic in Ensenada, Mexico |
| Intervention | Ibogaine treatment |
| Duration | Within 12 months of ibogaine treatment (median 169 days) |
| Topics | Ibogaine |
| Keywords | Ecology |
| Citations | 4 |
| Key findings | Ibogaine treatment alleviated cravings and withdrawal symptoms, prompted insight into addictions, and intersecting social-ecological experiences had an enduring impact on addiction recovery. |
Abstract
Abstract Background and aims Ibogaine, an alkaloid extracted from the root of the Tabernanthe Iboga shrub, holds promise in treating addictive disorders. Individuals receiving ibogaine treatment report decreased withdrawal symptoms, cravings, and addiction severity. These changes are often attributed to ibogaine's psychedelic properties: subjectively meaningful, dream-like experiences. Research demonstrates that ibogaine experiences impact multiple social-ecological dimensions and influence addiction and recovery trajectories. No studies have explored the multidimensional experiences of individuals seeking ibogaine treatment for addictions. The current study examines acute and enduring ibogaine experiences at individual, interpersonal, and behavioral health systems levels.
Methods: Fifteen individuals (5 female, 10 male) who received ibogaine treatment at a medical clinic in Ensenada, Mexico completed semi-structured interviews asking about individual, interpersonal, and behavioral health system experiences post-ibogaine within 12 months of ibogaine treatment ( Mdn = 169 days). Transcripts were coded and analyzed using a Consensual Qualitative Research approach.
Results: Many participants reported seeking ibogaine treatment after exhausting other addiction services. Outcomes reported following treatment included alleviated cravings and withdrawal symptoms. Participants indicated that ibogaine experiences prompted insight into their addictions and contributed to their recovery. Self-support and disclosing ibogaine experiences to professional and non-professional supporters were important to participants' recovery post-ibogaine.
Conclusions: Intersecting experiences across social-ecological levels had an enduring impact on participants' addiction recovery after ibogaine treatment. Despite negative experiences with behavioral health systems prior to receiving ibogaine treatment, most participants sought the support of mental health professionals post-ibogaine. Findings are informative for mental health professionals and clients interested in ibogaine treatment.
Comparable studies
Other qualitative studies on ibogaine, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The ibogaine medical subculture. Individuals who had taken ibogaine in the global medical subculture | 2008 | Ethnographic study with systematic quantitative data collection | n = 3,414 |
| A phenomenological analysis of the subjective experience elicited by ibogaine in the context of a drug dependence treatment Patients with substance-related disorders | 2017 | Qualitative study | n = 22 |
| A Mixed-Method Analysis of Persisting Effects Associated with Positive Outcomes Following Ibogaine Detoxification. Patients who received treatment for chronic opioid use in Mexico between 2012 and 2015 | 2018 | Retrospective mixed-methods study | n = 73 |
| Treating drug dependence with the aid of ibogaine: A qualitative study Patients with substance use disorders, including psychostimulant users | 2017 | Qualitative study | |
| A phenomenological investigation into the lived experience of ibogaine and its potential to treat opioid use disorders Individuals who underwent ibogaine treatment for an opioid use disorder | 2018 | Qualitative study |
Citations in the library
Cited by 3
- Reported Safety Practices of Publicly Advertised Psychedelic Retreats. JAMA Network Open January 2, 2026
- Psychedelics, rebirth experiences, and the limits of current research Psychedelics July 1, 2026
- The Ibogaine Experience Scale (IES): Development and psychometric properties of a multidimensional measure of ibogaine’s subjective effects PLoS One October 13, 2025
Cites 19
- Treatment of acute opioid withdrawal with ibogaine. American Journal on Addictions 1999
- Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum. Brain Research September 19, 1994
- Inhibitory effects of ibogaine on cocaine self-administration in rats. European Journal of Pharmacology September 14, 1993
- A preliminary investigation of ibogaine: case reports and recommendations for further study. Journal of Substance Abuse Treatment 1994
- Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes. The American Journal of Drug and Alcohol Abuse 2018
and 14 more in the library