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Magic mushroom compound shows promise against cocaine addiction

Rachel Nuwer

Science May 7, 2026 DOI: 10.1126/science.aei6155 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational (small study) Peer reviewed
Population Black and low-income participants
Topics Addiction Psilocybin
Key findings The study yielded remarkable results.

Abstract

Small study that prioritized Black and low-income participants yields "remarkable" results.

Comparable studies

Other observational and cohort studies on addiction, most cited first.

Study Year Design Participants
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population 2013 Observational study
Dynamic coupling of whole-brain neuronal and neurotransmitter systems Healthy humans 2020 Observational study
Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults 2015 Observational cohort n = 135,095
Breakdown of long-range temporal dependence in default mode and attention networks during deep sleep Human participants across the nonrapid eye movement sleep cycle 2013 Observational cohort
Assessment of addiction severity among ritual users of ayahuasca Regular ayahuasca users (jungle-based and urban-based) and matched controls 2010 Observational cohort n = 127

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