Skip to content

PAINscape—Exploring patient experiences with ketamine for chronic neuropathic pain: A qualitative study

Nandana D. Parakh, Danielle Lessor, Kevin Dang, Paul Ritvo, Duminda N Wijeysundera, Victoria Tucci, Mariela Leda, Mindy Lu, Gabriella Mattina, Janneth Pazmino-Canizares, Zaaria Thomas, Roshni Nayar, John G. Hanlon, Sérgio M. Pereira, Sunit Das, Hance Clarke, Sakina J. Rizvi, Cheryl Pritlove, Akash Goel

Canadian Journal of Pain March 4, 2026 DOI: 10.1080/24740527.2026.2615473 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative study Peer reviewed
Population Participants with chronic neuropathic pain
Intervention Ketamine infusions
Topics Ketamine Esketamine
Keywords Chronic pain Neuropathic pain Qualitative research Physical therapy Health care Medline
Key findings All participants reported decreased pain with ketamine infusions.

Abstract

Although pain experiences differed among participants, all participants reported decreased pain with ketamine infusions. Addressing the stigma associated with ketamine infusions, further research around augmenting durability of ketamine, and providing a safe treatment environment can all improve ketamine's benefit for chronic neuropathic pain. Understanding the barriers and facilitators, as well as implementing participant suggestions, will not only help inform our ketamine program but can improve access to pain management and facilitate future research in this field.

Comparable studies

Other qualitative studies on ketamine, most cited first.

Study Year Design Participants
Ketamine for Depression, 4: In What Dose, at What Rate, by What Route, for How Long, and at What Frequency? 2017 Qualitative review
Holding on or letting go? Patient experiences of control, context, and care in oral esketamine treatment for treatment-resistant depression: A qualitative study. Patients with treatment-resistant depression participating in off-label oral esketamine... 2022 Qualitative study n = 17
A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and Depression Healthcare providers 2022 Quality improvement evaluation with mixed methods n = 94
Predictors of Psychedelic Experience: A Thematic Analysis First-person reports of psychedelic use from the Erowid database (six reports each for... 2022 Thematic analysis n = 22
Expert Opinion on Psychedelic-Assisted Psychotherapy for People with Psychopathological Psychotic Experiences and Psychotic Disorders Experts in psychiatry, clinical psychology, medicine, and psychedelic effects 2024 Qualitative study n = 12

Citations in the library

Explore topics