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Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial.

Med August 13, 2026 DOI: 10.1016/j.medj.2026.101259 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Mixed-methods randomized pilot trial Pilot study Peer reviewed
Interventions Ketamine-assisted psychotherapy Ketamine
Topics Esketamine Ketamine Psychedelic-assisted therapy
Key findings Ketamine-assisted psychotherapy was feasible and acceptable for chronic neuropathic pain, with both groups experiencing reduced pain intensity and improved mood; qualitative findings suggest psychotherapy may add psychological benefits, but the pilot nature and small sample warrant larger trials.

Abstract

Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial.