Psilocybin-assisted psychotherapy for psycho-existential distress in advanced cancer: a narrative review
Luca Magnani, Luca Ghirotto, Fabio Fesce, Tania Simona Re, Silvia Tanzi, Mario Amore, Alessandra Costanza
BMJ Supportive & Palliative Care February 18, 2026 DOI: 10.1136/spcare-2025-005689 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Narrative review Peer reviewed |
|---|---|
| Population | Patients with advanced cancer |
| Intervention | Psilocybin-assisted psychotherapy |
| Topics | End-of-life distress Psilocybin Psychedelic-assisted therapy |
| Keywords | Psychotherapist Narrative review Psycho-oncology Palliative care Therapeutic relationship Grounded theory Psychological distress Qualitative research Medline Clinical psychology |
| Key findings | Psilocybin-assisted psychotherapy is a compelling therapeutic option that warrants further investigation for ethically grounded implementation in palliative care beyond oncology. |
Abstract
psilocybin-assisted psychotherapy is a compelling therapeutic option warranting further investigation through rigorous, interdisciplinary research to promote an anthropologically/ethically grounded implementation in palliative settings, even beyond the oncology field.