Mescaline: The forgotten psychedelic
Ian G Campbell, Ioanna A. Vamvakopoulou, Kelly A.d. Narine, Jason R.b. Dyck, David Nutt
Neuropharmacology October 14, 2022 DOI: 10.1016/j.neuropharm.2022.109294 (opens in new tab) via OpenAlex
Summary
AI-generated from the abstractMescaline's pharmacological mechanisms resemble those of other classical psychedelics such as psilocybin and LSD. Consumption appears safe, with most intoxications being mild and easily treatable. The substance may offer clinical benefits, including improvements in mental well-being and potential to help overcome alcoholism. This article is part of a special issue on psilocybin research.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | LSD Mescaline Psilocybin Serotonin |
| Keywords | Hallucinogen Psychotomimetic |
| Citations | 97 |
| Key finding | Mescaline appears safe and potentially beneficial in clinical settings, with mechanisms similar to other classical psychedelics. |
Abstract
The pharmacological mechanisms of mescaline are similar to those of other classical psychedelics, like psilocybin and lysergic acid diethylamide (LSD). Mescaline appears to be safe to consume, with most intoxications being mild and easily treatable. Improvement in mental well-being and its ability to overcome alcoholism render mescaline potentially beneficial in clinical settings. This article is part of the Special Issue on 'Psilocybin Research'.