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Mescaline: The forgotten psychedelic

Ian G Campbell, Ioanna A. Vamvakopoulou, Kelly A.d. Narine, Jason R.b. Dyck, David Nutt

Neuropharmacology October 14, 2022 DOI: 10.1016/j.neuropharm.2022.109294 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics LSD Mescaline Psilocybin Serotonin
Keywords Hallucinogen Psychotomimetic Euphoriant Pharmacology
Citations 97
Key findings Mescaline appears safe and potentially beneficial in clinical settings, with mechanisms similar to other classical psychedelics.

Abstract

The pharmacological mechanisms of mescaline are similar to those of other classical psychedelics, like psilocybin and lysergic acid diethylamide (LSD). Mescaline appears to be safe to consume, with most intoxications being mild and easily treatable. Improvement in mental well-being and its ability to overcome alcoholism render mescaline potentially beneficial in clinical settings. This article is part of the Special Issue on 'Psilocybin Research'.

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