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The Pharmacology of Mescaline and D-Lysergic Acid Diethylamide (LSD)

George B. Koelle

New England Journal of Medicine January 2, 1958 DOI: 10.1056/nejm195801022580106 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics LSD Mescaline
Keywords Schizophrenia object-oriented programming Mental disease Psychosis Freudian slip Hallucinogen Psychotherapist
Citations 18
Key findings Advances in laboratory methods and the biochemical defect found in phenylketonuria have renewed the search for a biochemical basis for schizophrenia and other psychoses.

Abstract

DURING the last few years a great revival of interest has occurred in the search for a biochemical basis for schizophrenia and the other types of psychosis. There are several reasons for this. Modern laboratory technics permit the detection and accurate quantitation of substances in the blood and tissues for which satisfactory procedures were not available formerly. The discovery of a partially correctable biochemical defect in one type of mental deficiency, phenylketonuria,1 has encouraged the hope that other forms of mental disease may be explained in similar terms. Many investigators believe that the Freudian concepts, with their emphasis on the . . .

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