Conformationally Constrained Analogs of Mescaline II
Robert J. Wolters, Ansuman Bej, N. S. Tanner
Journal of Pharmaceutical Sciences December 1, 1975 DOI: 10.1002/jps.2600641228 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Preclinical study Peer reviewed |
|---|---|
| Interventions | methyl-2-(3 4 5-trimethoxyphenyl)-2-(2-piperidyl) acetate |
| Topics | Mescaline |
| Keywords | Stereochemistry Pharmacology |
| Citations | 5 |
| Key points | The compound methyl-2-(3,4,5-trimethoxyphenyl)-2-(2-piperidyl) acetate was synthesized and compared pharmacologically with mescaline. |
Abstract
The synthesis of methyl-2-(3,4,5-trimethoxyphenyl)-2-(2-piperidyl) acetate is described. In addition, preliminary pharmacological data comparing the compound with mescaline are given.
Comparable studies
Other preclinical and animal studies on mescaline, most cited first.
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|---|---|---|---|
| Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species. C57BL/6J mice | 2020 | Experimental study with dose-response experiments | |
| Brain mechanisms of hallucinogens and entactogens Humans and rats | 2001 | Review | |
| Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology Zebrafish (Danio rerio) | 2012 | Experimental study | |
| Lysergic Acid Diethylamide- and Mescaline-Induced Attenuation of the Effect of Punishment in the Rat Rats | 1976 | Experimental study | |
| Dihydrobenzofuran Analogues of Hallucinogens. 3. Models of 4-Substituted (2,5-Dimethoxyphenyl)alkylamine Derivatives with Rigidified Methoxy Groups Rats (trained to discriminate saline from LSD tartrate) and rat cortical and... | 1996 | In vivo drug discrimination assay and in vitro radioligand binding assay |