An Aqueous-Organic Extraction Method for the Isolation and Identification of Psilocin from Hallucinogenic Mushrooms
Journal of Forensic Sciences 1985 DOI: 10.1520/jfs10989j (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Method development and validation Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Extraction chemistry Aqueous solution Gas chromatography–mass spectrometry Organic chemistry |
| Citations | 20 |
| Key points | A simple aqueous extraction method that dephosphorylates psilocybin to psilocin yields concentrated, contaminant-free psilocin suitable for identification by infrared spectroscopy and gas chromatography/mass spectrometry. |
Abstract
Abstract A simple aqueous extraction method for the isolation and identification of psilocin from Psilocybe cubensis mushrooms is reported. This method employs a dephosphorylation of the phosphate ester to psilocin, which facilitates a greater product yield and simplifies identification. Psilocin extracted by this method is sufficiently concentrated and free of cocontaminants to allow identification by infrared spectroscopy and gas chromatography/mass spectrometry.
Citations in the library
Cited by 17
- Fungal Hallucinogens Psilocin, Ibotenic Acid, and Muscimol Therapeutic Drug Monitoring July 12, 2013
- Identification of ω-N-Methyl-4-hydroxytryptamine (Norpsilocin) as a Psilocybe Natural Product Journal of Natural Products September 20, 2017
- Extraction and analysis of indole derivatives from fungal biomass Journal of Basic Microbiology 1994
- The Determination of Psilocin and Psilocybin in Hallucinogenic Mushrooms by HPLC Utilizing a Dual Reagent Acidic Potassium Permanganate and Tris(2,2′‐bipyridyl)ruthenium(II) Chemiluminescence Detection System Journal of Forensic Sciences 2006
- Occurrence and use of hallucinogenic mushrooms containing psilocybin alkaloids TemaNord May 19, 2009
and 12 more in the library
Cites 3
- Psilocybin und Psilocin, zwei psychotrope Wirkstoffe aus mexikanischen Rauschpilzen Helvetica Chimica Acta 1959
- Quantitative analysis of psilocybin and psilocin and psilocybe baecystis (singer and smith) by high-performance liquid chromatography and by thin-layer chromatography Journal of Chromatography A March 1, 1981
- Isolation of Psilocybin From Psilocybe argentipes and Its Determination in Specimens of Some Mushrooms Journal of Natural Products May 1, 1981