Chromatographic and mass spectrometric methods for determination of lysergic acid diethylamide (LSD) and metabolites in body fluids
Chad C. Nelson, Rodger L. Foltz
Journal of Chromatography B Biomedical Sciences and Applications September 1, 1992 DOI: 10.1016/0378-4347(92)80530-4 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | LSD |
| Keywords | Chromatography Detection limit |
| Citations | 46 |
| Key findings | Chromatographic and mass spectrometry methods can detect and quantify LSD at sub-nanogram/milliliter concentrations in body fluids. |
Abstract
Continued illicit use of the potent psychedelic drug lysergic acid diethylamide (LSD) has stimulated efforts to develop effective analytical methods for detection of the drug and its metabolites in body fluids from suspected LSD users. Recently reported methods based on gas and liquid chromatography, combined with single- and multiple-stage mass spectral analysis, now permit accurate detection and quantitation of LSD at sub-nanogram/milliliter concentrations.