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A Controlled Comparison of Lysergic Acid Diethylamide (LSD) and Dextroamphetamine in Alcoholics

Leo E. Hollister, Jack Shelton, George Krieger

American Journal of Psychiatry April 1, 1969 DOI: 10.1176/ajp.125.10.1352 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Controlled comparison Peer reviewed
Sample size 72
Population Alcoholic patients
Interventions LSD dextroamphetamine
Duration 6-month follow-up
Topics LSD
Keywords Dextroamphetamine Context archaeology Psychotherapist Clinical psychology
Citations 104
Key points LSD produced slightly better results early, but after six months both treatment groups had similar outcomes.

Abstract

Seventy-two alcoholic patients were admitted to a controlled comparison of LSD and dextroamphetamine as treatments. In the context of little associated psychotherapeutic intervention, LSD produced slightly better results early, but after six months the results were alike for both treatment groups. Controlled studies of such treatments are not only possible but mandatory, the authors conclude, if one is not to be misled into ascribing special therapeutic attributes to a specific treatment.

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