Assessing the psyhophysiological effects of Happy Tea at a Microdose Together company social event
Open Science Framework November 6, 2025 preprint DOI: 10.17605/osf.io/fmv2c (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Naturalistic observation |
|---|---|
| Intervention | Psilocybin truffles |
| Topics | Psilocybin |
| Keywords | Microdose Field mathematics Event particle physics Naturalistic observation Replicate Interpretation philosophy Applied psychology Cognitive psychology Developmental psychology |
| Key points | Psilocybin dose, trait absorption, and expectations influenced subjective experiences and neurophysiological outcomes in a naturalistic field setting, replicating lab-based effects. |
Abstract
We investigate how the dose of psilocybin truffles and participant characteristics (trait absorption and expectations) influence subjective experiences and neurophysiological outcomes in a naturalistic field setting.The aim is to replicate observed effects of psilocybin from lab-based and clinical studies in a field / naturalistic setting.
Comparable studies
Other observational and cohort studies on psilocybin, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression | 2017 | Observational cohort | n = 19 |
| Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels Healthy volunteers | 2019 | Observational cohort | n = 8 |
| Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin Humans | 2017 | Observational study | |
| Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. USA adult respondents from the National Survey on Drug Use and Health (2008-2012) | 2015 | Observational cohort | n = 190,000 |
| Prediction of Psilocybin Response in Healthy Volunteers Healthy volunteers | 2012 | Observational cohort | n = 409 |