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Is psilocybin only effective as part of psychotherapy?

Zenodo (CERN European Organization for Nuclear Research) January 22, 2026 DOI: 10.5281/zenodo.18339347 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Intervention Psilocybin
Topics Psilocybin
Keywords Pharmacology Intensive care medicine Medline Clinical trial Current fluid
Key findings Psilocybin is effective when combined with psychotherapy and may also have beneficial effects with less intensive psychological support.

Abstract

Current evidence mainly shows psilocybin's effectiveness when combined with psychotherapy, but there is also evidence suggesting it can have beneficial effects with less intensive psychological support. Further research is needed to clarify its efficacy as a standalone treatment.

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