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The therapeutic potential of psilocybin: a systematic review

Jan Van Amsterdam, Wim van den Brink

Expert Opinion on Drug Safety February 26, 2022 DOI: 10.1080/14740338.2022.2047929 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Double-blind Peer reviewed
Interventions Psilocybin Psychotherapy
Topics Psilocybin
Keywords Adverse effect Hallucinogen Placebo Randomized controlled trial Clinical trial
Citations 74
Key findings Psilocybin combined with psychotherapy shows promise for treating mental disorders, but larger double-blind RCTs with long-term outcomes are needed before standard clinical use.

Abstract

Psilocybin - mostly combined with psychotherapy or psychotherapeutic support - shows a promise as a treatment for various (treatment-resistant) mental disorders. Larger double-blind RCTs with objective (long-term) outcomes are needed to confirm these findings before standard clinical use of psilocybin can be considered.

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