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From Mushrooms to Myolysis

Mariella Suleiman, Arnabh Basu, Sameen Belal, Theresa Jacob

The Journal of Nervous and Mental Disease July 29, 2022 DOI: 10.1097/nmd.0000000000001489 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population A young patient who used a large amount of psilocybin
Intervention Psilocybin
Dose a large amount
Topics Psilocybin
Keywords Hallucinogen Psychosis Recreational drug Vigilance psychology Paranoia Amphetamine
Citations 8
Key findings Psilocybin use in a young patient was associated with a first psychotic and manic episode, violent behavior, and rhabdomyolysis.

Abstract

Abstract The involvement of certain recreational drugs, namely, hallucinogens, in the development of hyperactive syndromes is well known, but not well studied. In this report, we expand on this relationship by documenting the development of substance-induced psychosis in a young patient who used a large amount of psilocybin and developed symptoms of a first psychotic and manic episode, complicated by violent behavior and rhabdomyolysis. We further evaluate the association between psilocybin use and rhabdomyolysis and explore this understudied phenomenon and differentiate it from the diagnoses of other hyperactive syndromes seen in psychiatry. This case exemplifies the need for increased vigilance in psilocybin microdosing therapy and for physicians to be mindful of how each patient responds to its use to prevent life-threatening hyperactive syndromes in its wake.

Comparable studies

Other case reports and case series on psilocybin, most cited first.

Study Year Design Participants
Psilocybin Mushroom (Psilocybe semilanceata) Intoxication with Myocardial Infarction 18-year-old man 1998 Case study n = 1
Relief from intractable phantom pain by combining psilocybin and mirror visual-feedback (MVF) Person with leg amputation and phantom-limb pain 2018 Case study n = 1
Hallucinogen persisting perception disorder after psilocybin consumption: a case study 18-year-old man with HPPD after mixed psilocybin and cannabis intoxication 2005 Case study n = 1
Microdosing psilocybin for chronic pain: a case series Individuals with chronic neuropathic pain 2022 Case series n = 3
Psilocybin and Obsessive Compulsive Disorder Individual with Obsessive Compulsive Disorder 2014 Case study n = 1

Citations in the library

Cited by 7

and 2 more in the library

Cites 5

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