From Mushrooms to Myolysis
Mariella Suleiman, Arnabh Basu, Sameen Belal, Theresa Jacob
The Journal of Nervous and Mental Disease July 29, 2022 DOI: 10.1097/nmd.0000000000001489 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A young patient who used a large amount of psilocybin |
| Intervention | Psilocybin |
| Dose | a large amount |
| Topics | Psilocybin |
| Keywords | Hallucinogen Psychosis Recreational drug Vigilance psychology Paranoia Amphetamine |
| Citations | 8 |
| Key findings | Psilocybin use in a young patient was associated with a first psychotic and manic episode, violent behavior, and rhabdomyolysis. |
Abstract
Abstract The involvement of certain recreational drugs, namely, hallucinogens, in the development of hyperactive syndromes is well known, but not well studied. In this report, we expand on this relationship by documenting the development of substance-induced psychosis in a young patient who used a large amount of psilocybin and developed symptoms of a first psychotic and manic episode, complicated by violent behavior and rhabdomyolysis. We further evaluate the association between psilocybin use and rhabdomyolysis and explore this understudied phenomenon and differentiate it from the diagnoses of other hyperactive syndromes seen in psychiatry. This case exemplifies the need for increased vigilance in psilocybin microdosing therapy and for physicians to be mindful of how each patient responds to its use to prevent life-threatening hyperactive syndromes in its wake.