Exploring the relationship between mental health, drug use, personality, and attitudes towards psilocybin-assisted therapy
Benjamin M. Ross, James T. Neill
Journal of Psychedelic Studies August 21, 2023 DOI: 10.1556/2054.2023.00264 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional survey Peer reviewed |
|---|---|
| Sample size | 118 |
| Population | Young adults in the Australian Capital Territory |
| Topics | Anxiety LSD Psilocybin |
| Keywords | Taboo Clinical psychology Computer-assisted web interviewing Hallucinogen |
| Citations | 6 |
| Key findings | Openness to experience and recreational drug use are associated with more positive attitudes toward psilocybin-assisted therapy. |
Abstract
Abstract Background Psilocybin, the psychoactive compound in magic mushrooms, is increasingly discussed in terms of its psychotherapeutic potential; however, little is known about community attitudes towards psilocybin assisted therapy (PAT).
Aims: To address the question: What are the public's attitudes towards psilocybin and psilocybin-assisted therapy? And what factors explain these attitudes?
Methods: This study investigated the attitudes of 118 young adults in the Australian Capital Territory through an online survey.
Results: Participants who were more open to experience and who had used recreational drugs were more likely to have positive attitudes towards all aspects of PAT. Additionally, psychedelic drug use and agreeableness was positively associated with attitudes towards psilocybin safety, legality, and research; and psilocybin use was positively associated with attitudes towards psilocybin knowledge and acceptability.
Conclusions: This convenience sample of young adults was generally positively disposed towards PAT. People who were more open to experience and who had used recreational or psychedelic drugs had more favourable attitudes towards PAT.
Comparable studies
Other cross-sectional and survey studies on LSD for anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Anxiety and depression symptoms in Brazilian sexual minority ecstasy and LSD users Young Brazilian adults who used ecstasy and/or LSD in the past 90 days and were not in... | 2017 | Cross-sectional study | n = 240 |
| Faces of HPPD: Hallucinogen Persisting Perception Disorder Patient Survey Results and a Descriptive Analysis of Patient Demographics, Medical Background, Drug Use History, Symptoms, and Treatments Individuals diagnosed with hallucinogen persisting perception disorder (HPPD) from... | 2019 | Internet survey | n = 26 |
| Association of Hallucinogen Persisting Perception Disorder with Trait Neuroticism and Mental Health Symptoms. Hallucinogen and other drug users who completed an online questionnaire | 2025 | Cross-sectional survey | n = 415 |
Citations in the library
Cited by 6
- Supporting Meaningful Choices: A Decision Aid for Individuals Facing Existential Distress and Considering Psilocybin-Assisted Therapy Healthcare September 12, 2025
- Exploring Public Sentiments of Psychedelics Versus Other Substances: A Reddit-Based Natural Language Processing Study Journal of Psychoactive Drugs May 30, 2025
- Attitudes and perceptions of psychedelic therapy among clinical trial participants with alcohol use disorder: a mixed-method study Psychopharmacology June 10, 2026
- Classic psychedelics and personality: An updated systematic review. Journal of Psychopharmacology May 31, 2026
- ‘Go with the "wave of music" to dive deep’: Exploring perceptions of psychedelic-assisted therapy and the role of music within this practice The Arts in Psychotherapy March 1, 2025
and 1 more in the library
Cites 13
- Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later Journal of Psychopharmacology May 30, 2008
- Long-term follow-up of psilocybin-facilitated smoking cessation The American Journal of Drug and Alcohol Abuse July 21, 2016
- The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act Neuropharmacology June 5, 2018
- The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis Psychiatry Research January 2, 2020
- Psychedelics, Personality and Political Perspectives. Journal of Psychoactive Drugs April 26, 2017
and 8 more in the library