Psilocybin-induced takotsubo cardiomyopathy
Wiktoria Julia Kotts, David Gamble, Dana Dawson, David E. Connor
BMJ Case Reports May 1, 2022 DOI: 10.1136/bcr-2021-245863 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Patient who ingested Psilocybe semilanceata |
| Topics | Psilocybin |
| Keywords | Cardiomyopathy Takotsubo syndrome Cardiology Hallucinogen Electroconvulsive therapy studies |
| Citations | 10 |
| Key findings | Takotsubo cardiomyopathy can occur after ingestion of Psilocybe semilanceata, with this being the second reported case. |
Abstract
We present a case of takotsubo cardiomyopathy following recreational ingestion of Psilocybe semilanceata (known as ‘magic mushrooms’). The patient presented with respiratory distress and pulmonary oedema responding to standard medical measures. Investigations included: echocardiogram, cardiac MRI and angiogram. Based on our search, we suggest this is only the second recognised case in the published literature.
Comparable studies
Other case reports and case series on psilocybin, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psilocybin Mushroom (Psilocybe semilanceata) Intoxication with Myocardial Infarction 18-year-old man | 1998 | Case study | n = 1 |
| Relief from intractable phantom pain by combining psilocybin and mirror visual-feedback (MVF) Person with leg amputation and phantom-limb pain | 2018 | Case study | n = 1 |
| Hallucinogen persisting perception disorder after psilocybin consumption: a case study 18-year-old man with HPPD after mixed psilocybin and cannabis intoxication | 2005 | Case study | n = 1 |
| Microdosing psilocybin for chronic pain: a case series Individuals with chronic neuropathic pain | 2022 | Case series | n = 3 |
| Psilocybin and Obsessive Compulsive Disorder Individual with Obsessive Compulsive Disorder | 2014 | Case study | n = 1 |
Citations in the library
Cited by 5
- Cardiovascular safety of psychedelic medicine: current status and future directions Pharmacological Reports October 24, 2023
- Psilocybin for the treatment of Alzheimer’s disease Frontiers in Neuroscience July 10, 2024
- Psychedelics, With a Focus on Psilocybin: Issues for the Clinician. Journal of Psychiatric Practice September 1, 2023
- Cardiac Arrest Associated With Psilocybin Use and Hereditary Hemochromatosis Cureus May 7, 2023
- Primum Non Nocere: The Onus to Characterize the Potential Harms of Psychedelic Treatment. American Journal of Psychiatry 2025
Cites 3
- The pharmacology of psilocybin Addiction Biology October 1, 2002
- Psilocybin Mushroom (Psilocybe semilanceata) Intoxication with Myocardial Infarction Journal of Toxicology Clinical Toxicology 1998
- Apical regional wall motion abnormalities reminiscent to Tako-Tsubo cardiomyopathy following consumption of psychoactive fungi. International journal of cardiology May 1, 2009