Belief changes associated with psychedelic use.
Sandeep M. Nayak, Manvir Singh, David B. Yaden, Roland R. Griffiths
Journal of Psychopharmacology 2023 DOI: 10.1177/02698811221131989 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Survey Qualitative Peer reviewed |
|---|---|
| Sample size | 2,374 |
| Population | Respondents who endorsed having had a belief-changing psychedelic experience |
| Duration | Average 8.4 years follow-up |
| Keywords | 5-ht2a receptor agonist Psychedelics Beliefs |
| Citations | 87 |
| Key findings | A single psychedelic experience increased a range of non-physicalist beliefs, and the magnitude of change was associated with qualitative features of the experience. |
Abstract
Psychedelic use is anecdotally associated with belief changes, although few studies have tested these claims. Characterize a broad range of psychedelic occasioned belief changes. A survey was conducted in 2374 respondents who endorsed having had a belief changing psychedelic experience. Participants rated their agreement with belief statements Before and After the psychedelic experience as well as at the time of survey administration. Factor analysis of 45 belief statements revealed five factors: "Dualism," "Paranormal/Spirituality," "Non-mammal consciousness," "Mammal consciousness," and "Superstition." Medium to large effect sizes from Before to After the experience were observed for increases in beliefs in "Dualism" (β = 0.72), "Paranormal/Spirituality" (β = 0.90), "Non-mammal consciousness" (β = 0.72), and "Mammal consciousness" (β = 0.74). In contrast, negligible changes were observed for "Superstition" (β = -0.18).). At the individual item level, increases in non-physicalist beliefs included belief in reincarnation, communication with the dead, existence of consciousness after death, telepathy, and consciousness of inanimate natural objects (e.g., rocks). The percentage of participants who identified as a "Believer (e.g., in Ultimate Reality, Higher Power, and/or God, etc.)" increased from 29% Before to 59% After." At both the factor and individual item level, higher ratings of mystical experience were associated with greater changes in beliefs. Belief changes assessed after the experience (an average 8.4 years) remained largely unchanged at the time of survey. A single psychedelic experience increased a range of non-physicalist beliefs as well as beliefs about consciousness, meaning, and purpose. Further, the magnitude of belief change is associated with qualitative features of the experience.
Citations in the library
Cited by 68
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- An Integrated theory of false insights and beliefs under psychedelics. Communications Psychology August 1, 2024
- Distinctive But Not Exceptional: The Risks of Psychedelic Ethical Exceptionalism. The American Journal of Bioethics 2025
- Navigating groundlessness: An interview study on dealing with ontological shock and existential distress following psychedelic experiences. PLoS One 2025
- Unique Psychological Mechanisms Underlying Psilocybin Therapy Versus Escitalopram Treatment in the Treatment of Major Depressive Disorder International Journal of Mental Health and Addiction March 7, 2024
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Cites 17
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- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder JAMA Psychiatry November 4, 2020
- REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics Pharmacological Reviews June 20, 2019
- Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects. Psychopharmacology December 1, 2011
- Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later Journal of Psychopharmacology May 30, 2008
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