Psychedelics and Evidence-based Psychotherapy: A Systematic Review with Recommendations for Advancing Psychedelic Therapy Research.
Lewis Leone, Bryan McSpadden, Annamarie Demarco, Lauren Enten, Rachel Kline, Gregory A. Fonzo
The Psychiatric clinics of North America June 1, 2024 DOI: 10.1016/j.psc.2024.02.006 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Peer reviewed |
|---|---|
| Topics | Psychedelic-assisted therapy |
| Keywords | Evidence-based treatment Psychedelics Treatment development |
| Key findings | There is no consensus on how to best integrate the psychedelic experience with evidence-based psychotherapeutic treatment, and the review provides recommendations for combining psychotherapy with psychedelics. |
Abstract
Administration of psychedelics for mental health treatment, typically referred to as "psychedelic-assisted therapy," is a broad term with a very heterogeneous implementation. Despite increasing interest in the clinical application of psychedelic compounds for psychiatric disorders, there is no consensus on how to best integrate the psychedelic experience with evidence-based psychotherapeutic treatment. This systematic review provides a timely appraisal of existing approaches to combining psychotherapy with psychedelics and provides clear recommendations to best develop, optimize, and integrate evidence-based psychotherapy with psychedelic administration for straightforward scientific inference and maximal therapeutic benefit.