Mindfulness-based cognitive therapy improves insomnia symptoms in individuals with recurrent depression: secondary analyses from a randomized controlled trial.

Linn Nyjordet Evanger; Elisabeth Flo-Groeneboom; Lin Sørensen; Elisabeth Schanche

doi:10.3389/fpsyt.2023.1231040

Mindfulness-based cognitive therapy improves insomnia symptoms in individuals with recurrent depression: secondary analyses from a randomized controlled trial.

Linn Nyjordet Evanger, Elisabeth Flo-Groeneboom, Lin Sørensen, Elisabeth Schanche

Frontiers in Psychiatry 2023 DOI: 10.3389/fpsyt.2023.1231040 (opens in new tab)

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Study at a glance

AI-extracted from the abstract

Characteristics	Randomized controlled trial Peer reviewed
Sample size	55
Population	Remitted adults with recurrent depression (at least three prior episodes)
Intervention	Mindfulness-based cognitive therapy
Duration	8-week intervention
Topics	Meditation Depression
Keywords	Insomnia Psychotherapy Recurrent depression Sleep
Citations	9
Key findings	MBCT significantly reduced insomnia severity, sleep onset problems, and nocturnal awakenings compared to a waitlist control, but did not improve early morning awakening, daytime impairment, or sleep dissatisfaction.

Abstract

Embedded within a randomized efficacy trial, the present study aimed to investigate whether mindfulness-based cognitive therapy (MBCT) for recurrent depression improved symptoms of insomnia. Sixty-eight remitted participants with at least three prior episodes of depression were randomized to 8 weeks of MBCT (n = 33) or a waitlist control condition (n = 35). The Bergen Insomnia Scale was used to screen for insomnia symptoms before and after the intervention. The analyses were conducted using one-way between-groups analyses of covariance. Twenty-five MBCT participants and 30 waitlist controls completed the study (74.5% females; mean age 40.7 ± 12.9 years). At baseline, 83.6% screened positive for the insomnia diagnosis. Following the intervention and after controlling for corresponding insomnia parameters at baseline, MBCT completers reported significantly less severe insomnia symptoms (p = 0.017), as well as less problems with prolonged sleep onset (p = 0.047) and nocturnal awakenings (p = 0.023), relative to controls. No group differences were found on early morning awakening, daytime impairment, or dissatisfaction with sleep. The results suggest that MBCT improves certain insomnia symptoms. However, additional sleep-specific interventions may be needed to further improve this population's sleep.Clinical Trial Registration: ISRCTN, ISRCTN18001392, registered 22/11/2018. URL: 10.1186/ISRCTN18001392.

Comparable studies

Other randomized controlled trials on depression, most cited first.

Study	Year	Design	Participants
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression Subjects with DSM-IV major depression (treatment resistant)	2006	Randomized, placebo-controlled, double-blind crossover study	n = 18
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients	2000	Randomized controlled trial	n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety	2016	Randomized controlled trial	n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression	2016	Double-blind, placebo-controlled, crossover trial	n = 29
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients	2004	Randomized controlled trial	n = 73

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