Reduction of alcohol use and increase in psychological flexibility after a naturalistic psychedelic experience: a retrospective survey.
Ewen Kervadec, Baptiste Fauvel, Lana Strika-Bruneau, Ammar Amirouche, Vincent Verroust, Pascale Piolino, Bruno Romeo, Amine Benyamina
Alcohol and Alcoholism January 17, 2024 DOI: 10.1093/alcalc/agad078 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Retrospective online survey Peer reviewed |
|---|---|
| Sample size | 160 |
| Population | Individuals who reported a psychedelic experience and a concomitant drinking habit |
| Intervention | Psychedelic experience |
| Topics | Addiction |
| Keywords | Drinking Psychedelic Psychological flexibility |
| Citations | 15 |
| Key findings | A naturalistic psychedelic experience was associated with a significant reduction in drinking days per week and AUDIT scores, with the reduction linked to the intensity of the mystical experience and increases in psychological flexibility. |
Abstract
Alcohol use can be significantly associated with negative social, professional, and health outcomes. Even more so, alcohol use disorder (AUD) is a critical public health issue and major avoidable risk factor. This study aimed to examine the effect of a naturalistic psychedelic experience on alcohol use and related measures. A retrospective online survey was conducted on 160 individuals who reported a psychedelic experience and a concomitant drinking habit but did not necessarily have an AUD. Demographic data, characteristics of the psychedelic experience, and changes in alcohol consumption and psychological flexibility were surveyed.
Results: The mean number of drinking days per week and AUDIT scores significantly decreased after the psychedelic experience (P < .001). Subjects who quit or reduced drinking had a more severe AUD (P < .01) and lower psychological flexibility (P = .003) before the psychedelic session. Alcohol use reduction was significantly associated with the intensity of the mystical experience (P = .03). Psychological flexibility increased more in participants who reduced their alcohol use (P < .001), and the change in psychological flexibility was one of the predictors of alcohol use improvement (P = .003).
Conclusion: Our findings suggest that a naturalistic psychedelic experience could be associated with a reduction in alcohol use and dependency. Such positive health outcomes can be associated with the intensity of the mystical experience as well as an increase in psychological flexibility.
Comparable studies
Other cross-sectional and survey studies on addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey Online survey respondents | 2020 | Cross-sectional survey | |
| The users of Novel Psychoactive Substances: Online survey about their characteristics, attitudes and motivations International users of novel psychoactive substances recruited via bluelight.org | 2016 | Cross-sectional online survey | n = 619 |
| User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study Users of hallucinogenic drugs who completed a web-based questionnaire | 2010 | Cross-sectional survey | n = 600 |
| Psychological and neuropsychological assessment of regular hoasca users. Regular hoasca users from a U.S. branch of União do Vegetal and matched non-user controls | 2016 | Cross-sectional study | n = 57 |
| Client and counselor attitudes toward the use of medications for treatment of opioid dependence. Counselors and clients from outpatient, methadone, and residential drug treatment programs | 2007 | Cross-sectional survey | n = 1,459 |
Citations in the library
Cited by 16
- The intensity of the psychedelic experience is reliably associated with clinical improvements: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews May 1, 2025
- Psychedelic substitution: altered substance use patterns following psychedelic use in a global survey. Frontiers in Psychiatry 2024
- The potential of 5‐methoxy‐N,N‐dimethyltryptamine in the treatment of alcohol use disorder: A first look at therapeutic mechanisms of action Addiction Biology April 1, 2024
- A Scoping Review of Research in Naturalistic Studies with Psychedelics. Journal of Psychoactive Drugs June 28, 2025
- Pattern of psychedelic substance use: a comparison between populations in Spain and South America using the Psychedelic Use Scale (PUS) Current Psychology November 21, 2024
and 11 more in the library
Cites 37
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Journal of Psychopharmacology November 30, 2016
- Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Journal of Psychopharmacology November 30, 2016
- Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry May 17, 2016
- Trial of Psilocybin versus Escitalopram for Depression New England Journal of Medicine April 14, 2021
- Mindfulness and acceptance: expanding the cognitive-behavioral tradition Choice Reviews Online July 1, 2005
and 32 more in the library