The gamma-band activity model of the near-death experience: a critique and a reinterpretation.
Nigel A Shaw
F1000Research 2024 DOI: 10.12688/f1000research.151422.2 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | Near-death experience |
| Keywords | Amygdala Consciousness Electroencephalogram Electromyogram Gamma oscillations |
| Citations | 2 |
| Key points | Argues that the perimortem surge of gamma-band activity, while genuine, likely originates subcortically and provides little evidence to support it as the neural foundation of near-death experiences. |
Abstract
Near-death experience (NDE) is a transcendent mental event of uncertain etiology that arises on the cusp of biological death. Since the discovery of NDE in the mid-1970s, multiple neuroscientific theories have been developed in an attempt to account for it in strictly materialistic or reductionistic terms. Therefore, in this conception, NDE is at most an extraordinary hallucination without any otherworldly, spiritual, or supernatural denotations. During the last decade or so, a number of animal and clinical studies have emerged which reported that about the time of death, there may be a surge of high frequency electroencephalogram (EEG) at a time when cortical electrical activity is otherwise at a very low ebb. This oscillatory rhythm falls within the range of the enigmatic brain wave-labelled gamma-band activity (GBA). Therefore, it has been proposed that this brief, paradoxical, and perimortem burst of the GBA may represent the neural foundation of the NDE. This study examines three separate but related questions concerning this phenomenon. The first problem pertains to the electrogenesis of standard GBA and the extent to which authentic cerebral activity has been contaminated by myogenic artifacts. The second problem involves the question of whether agents that can mimic NDE are also underlain by GBA. The third question concerns the electrogenesis of the surge in GBA itself. It has been contended that this is neither cortical nor myogenic in origin. Rather, it arises in a subcortical (amygdaloid) location but is recorded at the cortex via volume conduction, thereby mimicking standard GBA. Although this surge of GBA contains genuine electrophysiological activity and is an intriguing and provocative finding, there is little evidence to suggest that it could act as a kind of neurobiological skeleton for a phenomenon such as NDE.
Comparable studies
Other theoretical and historical papers on near-death experience, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Otherworld Journeys: Accounts of Near-Death Experience in Medieval and Modern Times | 1987 | Historical analysis | |
| Neuroscience and the Near-Death Experience: Roles for the NMSA-PCP receptor, the sigma receptor and the endopsychosins | 1990 | Theoretical or philosophical paper | |
| Implications of near-death experiences for a postmaterialist psychology. | 2010 | Theoretical or philosophical paper | |
| Near-Death Experience as a Probe to Explore (Disconnected) Consciousness | 2020 | Theoretical or philosophical paper | |
| Near-death experiences between science and prejudice | 2012 | Theoretical or philosophical paper |
Citations in the library
Cites 19
- Near-death experience in survivors of cardiac arrest: a prospective study in the Netherlands The Lancet December 1, 2001
- Neural correlates of the DMT experience assessed with multivariate EEG. Scientific Reports November 19, 2019
- DMT Models the Near-Death Experience Frontiers in Psychology August 15, 2018
- Human brain effects of DMT assessed via EEG-fMRI. Proceedings of the National Academy of Sciences March 28, 2023
- Does the arousal system contribute to near death experience? Neurology April 10, 2006
and 14 more in the library