Yoga an integrated mind body intervention for improvement in quality of life in individuals with Alzheimer's disease and their caregivers.
Meenakshi Kaushik, Anjali Yadav, Ashishdatt Upadhyay, Anu Gupta, Prabhakar Tiwari, Manjari Tripathi, Rima Dada
Frontiers in aging 2025 DOI: 10.3389/fragi.2025.1449485 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Interventional study Peer reviewed |
|---|---|
| Sample size | 30 |
| Population | Adults aged 60 years or older with mild to moderate Alzheimer's disease from an old age home |
| Intervention | pranayama |
| Duration | 12-week intervention |
| Topics | Meditation |
| Keywords | Alzheimer’s disease Gds &moca scales Caregiver burden Quality of life Yoga |
| Citations | 14 |
| Key points | A 12-week yoga intervention significantly improved depression and cognitive function in individuals with mild to moderate Alzheimer's disease and reduced caregiver burden. |
Abstract
Alzheimer's disease (AD) presents profound challenges, significantly impairing quality of life (QOL) for patients and increasing the burden on caregivers. This study aims to investigate the effectiveness of a tailored 12-week yoga intervention in improving the quality of life for individuals with mild to moderate AD and reducing caregiver burden (CB). This is yoga interventional study with healthy controls enrolled 30 participants (18 males, 12 females) diagnosed with mild to moderate AD by an expert neurologist. Participants were aged 60 years or older and were recruited from an old age home. A 12-week yoga program, including specific postures (asanas), pranayama (breathing exercises), and meditation, was conducted for 1 hour daily, 6 days a week. Neurocognitive assessments were performed pre- and post-intervention using the Geriatric Depression Scale (GDS), Montreal Cognitive Assessment (MoCA), and Caregiver Burden (CB) Scale. MoCA scores were analyzed across specific domains, including language, memory, attention, visuospatial ability, delayed recall, abstraction, and orientation. The intervention led to significant improvements in quality-of-life measures. GDS scores decreased from 8.36 ± 2.79 to 5.13 ± 3.07 (P < 0.01; 95% CI: -3.98 to -2.31), while MoCA total scores improved from 18.23 ± 4.90 to 21.10 ± 5.09 (P < 0.01; 95% CI: 2.17-3.89). Domain-specific MoCA scores also showed significant enhancements, particularly in language, attention, and delayed recall. Caregiver burden, measured using the CB Scale, demonstrated notable reductions following the intervention (P < 0.01; 95% CI: -2.54 to -1.23). This study underscores the significant improvements in depression and cognitive function, and overall quality of life in individuals with mild to moderate AD. Additionally, the intervention alleviated caregiver burden, highlighting its potential as an effective mind-body approach for AD management.