Effect of online mindfulness intervention on anxiety, depression, and stress in patients with chronic diseases.
Ying-Ju Chen, Chiu-Hsiang Lee, Chia-Jung Hsieh, Pei-Hung Liao, Yu-Da Chen, Kuei-Ru Chou, Shu-Liu Guo, Li-Fang Chang, Tso-Ying Lee
Explore (New York, N.Y.) July 8, 2025 DOI: 10.1016/j.explore.2025.103214 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Qualitative Peer reviewed |
|---|---|
| Sample size | 97 |
| Population | Patients with chronic diseases |
| Intervention | Online mindfulness platform |
| Duration | 8-week intervention, assessments at baseline, 4 weeks, and 8 weeks |
| Topics | Anxiety Depression Meditation |
| Keywords | Adults Chronic disease Online mindfulness platform Stress |
| Citations | 1 |
| Key findings | Online mindfulness intervention significantly reduced anxiety at 4 and 8 weeks, and reduced depression and stress at 8 weeks, in adults with chronic diseases. |
Abstract
Online mindfulness may be an effective non-pharmacological mental health intervention. To evaluate the effectiveness of an online mindfulness platform in ameliorating anxiety, depression, and stress in patients with chronic diseases. In this randomized controlled study, 97 patients were enrolled and randomly assigned to either the online intervention group (N = 47) or the control group (N = 50). Anxiety, depression, and stress levels were assessed at baseline, 4 weeks, and 8 weeks after the intervention. The baseline scores of anxiety, depression, and stress between the control and experiment groups were comparable. Online mindfulness intervention significantly reduced anxiety scores at Week 4 and Week 8 (both P < 0.001). In addition, online mindfulness intervention significantly lowered both depression scores and stress levels at Week 8 (both P ≤ 0.002), but not at Week 4. Online mindfulness interventions effectively alleviate anxiety, depression, and stress in patients with chronic diseases. Future qualitative research is recommended to further explore the mechanisms of change at the psychological level.