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Comparing Cannabis Use Motivations and Dependence Across Regular Cannabis Users Who Have or Have Not Recently Used Psilocybin

Madeline K Stanger, Harmony O Soffer, Angela D Bryan, Carillon J. Skrzynski

Cannabis and Cannabinoid Research June 17, 2024 DOI: 10.1089/can.2024.0059 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Sample size 97
Population Regular cannabis users (use ≥7 times/month) in Colorado, 35.1% female, 89.7% White
Topics Cannabis Psilocybin Addiction
Keywords Cannabis use motives Coping Polydrug use Polydrug behavior Drug interaction Substance use patterns Cannabis consumption Psychedelic research
Citations 1
Key findings Individuals who recently used psilocybin had higher cannabis dependence scores and more strongly endorsed cannabis use for enjoyment, boredom, and altered experience motives than those who had not used psilocybin recently.

Abstract

Introduction: In Colorado, both cannabis and psilocybin are legal and becoming more commonly used. However, there is almost no research detailing the public health concerns regarding negative outcomes (e.g., dependence) of cannabis and psilocybin co-use and motives that may perpetuate these negative outcomes (e.g., coping, boredom).

Methods: Using data from a larger observational study on cannabis and metabolic processes, regular cannabis users (use ≥7 times/month; n = 97, 35.1% female, 89.7% WHITE) who used psilocybin in the past 3 months (n = 34) were compared with those who had not used psilocybin in the past 3 months (n = 63) on cannabis dependence as measured by the Marijuana Dependence Scale and endorsement of 12 cannabis motives from the Comprehensive Marijuana Motives Questionnaire. Correlations between motives and dependence were also examined and compared across groups.

Results: Findings revealed that individuals who had recently used psilocybin had greater cannabis dependence scores than those who had not used recently [F (1, 95) = 5.53, p = 0.02], and more strongly endorsed that their cannabis use was motivated by enjoyment [F (1, 91) = 4.31, p = 0.04], boredom [F (1, 91) = 9.10, p F (1, 91) = 9.46, p p values p values

Discussion: These results suggest there are motivational differences for cannabis use among those who co-use cannabis and psilocybin, and there may be a greater risk for harm for these individuals.

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