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Postgraduate Medical Journal

ISSN 1469-0756, 0032-5473

6 papers in the library · 135 citations · publishing 1981-2024

Papers

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An evaluation of the efficacy and side effects of a single dose of ketamine in major depressive disorder.

Postgraduate Medical Journal October 14, 2024 Betül Uyar, Mehmet Güneş 1 citation

This study aims to provide a comprehensive overview of the antidepressant and antisuicidal efficacy of ketamine in patients with unipolar depression, with a focus on the clinical evidence and safety profile. In our study, the data of 120 major depressive disorder patients who received single-dose ketamine infusion therapy were evaluated retrospectively, with Montgomery-Asberg Depression Rating...

DOI: 10.1093/postmj/qgae142 (opens in new tab) Full text (opens in new tab) Single dose Suicide Depression treatment Ketamine therapy +3

Emergence of free will and consciousness in humans: implications for doctor-patient interactions.

Postgraduate Medical Journal June 2018 Philip D Welsby

Human brains have about 100 billion neurons each with about 1000 dendritic connections with other neurons giving a total of 100 000 billion deterministic dendritic switches. Various voting systems that the brain may use can produce conflicting results from identical inputs without any indication as to which one or ones would be correct. Voting systems cannot deliver unequivocal results in any...

DOI: 10.1136/postgradmedj-2018-135634 (opens in new tab) Full text (opens in new tab) Consciousness Free will Informed consent Voting systems

Cerebral infarction in association with Ecstasy abuse

Postgraduate Medical Journal November 1, 1993 Smita Manchanda, Michael Connolly 76 citations

A previously fit 35 year old man presented with a right hemiparesis and dysphasia 36 hours after abuse of Ecstasy (3,4-methylenedioxymethamphetamine). Computerized axial tomography scan demonstrated an extensive acute left cerebral infarction and carotid digital subtraction angiogram, 2 days after admission, revealed left middle cerebral artery occlusion. There were no other known risk factors...

Analgesic nitrous oxide for alcohol withdrawal: a critical appraisal after 10 years' use.

Postgraduate Medical Journal July 1990 M A Gillman, F J Lichtigfeld

We describe a method of treating the mild to moderate alcohol withdrawal state which has been used successfully for 10 years in over 7,000 cases. It is now the standard therapy at the largest dedicated alcoholic rehabilitation centre in Southern Africa. The technique uses analgesic (subanaesthetic) concentrations of nitrous oxide, which in most cases is administered on a single occasion for 20...

Clinical toxicology of ‘magic mushroom’ ingestion

Postgraduate Medical Journal September 1, 1981 Norman R. Peden, Katrina Macaulay, Ann F Bissett et al. 58 citations

Summary The clinical features are reported in 27 cases of ‘magic mushroom’ ingestion. Mydriasis and hyperreflexia were common as were disorders of perception and affect. Psilocybe semilanceata appears to have been the species of fungus involved.

DOI: 10.1136/pgmj.57.671.543 (opens in new tab) Full text (opens in new tab) Mushroom poisoning Ingestion Mydriasis Clinical toxicology +7