ISSN 1469-0756
2 papers in the library · 59 citations · publishing 1981-2024
Postgraduate Medical Journal September 1, 1981 N. R. Peden, Katrina Macaulay, Ann F Bissett et al. 58 citations
In 27 cases of magic mushroom ingestion, common physical signs included dilated pupils (mydriasis) and overactive reflexes (hyperreflexia), along with disturbances in perception and mood. The fungus involved was likely Psilocybe semilanceata.
Postgraduate Medical Journal October 14, 2024 Betül Uyar, Mehmet Güneş 1 citation
A single dose of ketamine infusion rapidly reduces both depressive symptoms and suicidal thoughts in people with major depressive disorder. In a retrospective evaluation of 120 patients, depression scores measured by the Montgomery-Asberg Depression Rating Scale (MADRS) and a suicide-specific subscale dropped significantly within 4 hours and remained lower at 24 hours after treatment. The improvements occurred regardless of sex, treatment resistance, or history of suicide attempts. The findings align with prior evidence that ketamine can produce fast-acting antidepressant effects, even in severe, treatment-resistant cases. The reduction in suicidal ideation is especially important because few interventions work quickly during acute suicidal crises.