Cerebral infarction in association with Ecstasy abuse
Smita Manchanda, Michael Connolly
Postgraduate Medical Journal November 1, 1993 DOI: 10.1136/pgmj.69.817.874 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A previously fit 35-year-old man who abused Ecstasy |
| Interventions | Ecstasy (3 4-methylenedioxymethamphetamine) |
| Topics | MDMA |
| Citations | 76 |
| Key findings | The authors propose an association between Ecstasy (MDMA) abuse and cerebral infarction, based on a previously fit 35-year-old man who suffered an extensive left cerebral infarction with left middle cerebral artery occlusion 36 hours after Ecstasy use, with no other identified risk factors and a partial recovery. |
Abstract
A previously fit 35 year old man presented with a right hemiparesis and dysphasia 36 hours after abuse of Ecstasy (3,4-methylenedioxymethamphetamine). Computerized axial tomography scan demonstrated an extensive acute left cerebral infarction and carotid digital subtraction angiogram, 2 days after admission, revealed left middle cerebral artery occlusion. There were no other known risk factors and all other investigations were negative. The patient made a partial recovery. We propose an association between Ecstasy abuse and cerebral infarction.
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cited by 8
- Pathology of deaths associated with "ecstasy" and "eve" misuse. Journal of Clinical Pathology February 1, 1996
- MDMA-assisted therapy: A new treatment model for social anxiety in autistic adults. Progress in Neuro-Psychopharmacology and Biological Psychiatry January 4, 2016
- Deconstructing Ecstasy: The Politics Of Mdma Research Addiction Research & Theory 2000
- Cerebral vasculopathy after 4-bromo-2,5-dimethoxyphenethylamine ingestion. The neurologist May 1, 2010
- The entactogen 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) as a treatment aid in psychotherapy and its safety concerns. Archives of Toxicology August 1, 2024
and 3 more in the library