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Wiley Interdisciplinary Reviews Membrane Transport and Signalling

ISSN 2190-460X

1 paper in the library · 80 citations · publishing 2012

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Structure–activity relationships of serotonin 5‐HT2Aagonists

Wiley Interdisciplinary Reviews Membrane Transport and Signalling February 28, 2012 David E. Nichols 80 citations

Abstract Of the 14 known types of serotonin receptors one of the most extensively studied is the 5‐HT 2A (5‐hydroxytryptamine) receptor. In the brain, this receptor plays a key role in regulation of cortical function and cognition, appears to be the principal target for the hallucinogenic/psychedelic drugs such as lysergic acid diethylamide (LSD), and also is a target for the newest atypical...