Journal of Affective Disorders
January 15, 2015
Giovanni Stanghellini, Andrea Raballo
It is a current trend in psychiatry to discard the Kraepelinian dichotomy schizophrenia vs. manic-depressive illness and use the overinclusive label 'psychosis' to broadly indicate the whole spectrum of severe mental disorders. In this paper we show that the characteristics of psychotic symptoms vary across different diagnostic categories. We compare delusions in schizophrenia and major...
Journal of Affective Disorders
February 18, 2014
D. Luckenbaugh, Mark J. Niciu, Dawn F. Ionescu et al.
282 citations
Background The N-methyl-D-aspartate receptor antagonist ketamine has rapid antidepressant effects in major depression. Psychotomimetic symptoms, dissociation and hemodynamic changes are known side effects of ketamine, but it is unclear if these side effects relate to its antidepressant efficacy. Methods Data from 108 treatment-resistant inpatients meeting criteria for major depressive disorder...
Journal of Affective Disorders
July 2013
Amrita Sandhu, Jonathan Ives, Max J. Birchwood et al.
Depression following first episode psychosis (FEP) is a frequent occurrence, with profound impact on recovery and outcome. Whilst many theories exist about the causes of depression here, research to date has been based on nosology imported wholesale from affective disorder, with little primary research on the subjective experience. This study aimed to explore the subjective experience and...
Journal of Affective Disorders
June 20, 2013
Victoria L Ives-Deliperi, Fleur M Howells, Dan J Stein et al.
Background: Preliminary research findings have shown that mindfulness-based cognitive therapy improves anxiety and depressive symptoms in bipolar disorder. In this study, we further investigated the effects of MBCT in bipolar disorder, in a controlled fMRI study. Method: Twenty three patients with bipolar disorder underwent neuropsychological testing and functional MRI. Sixteen of these...
Journal of Affective Disorders
June 25, 2011
Mindfulness, response styles and dysfunctional attitudes in bipolar disorder.
Journal of Affective Disorders
November 20, 2010
Mindfulness-based cognitive therapy vs cognitive behaviour therapy as a treatment for non-melancholic depression.
Journal of Affective Disorders
October 2010
Giovanni Stanghellini, René Rosfort
The complex relationship between temperament and personal identity, and between these and mental disorders, is of critical interest to both philosophy and psychopathology. More than other living creatures, human beings are constituted and characterized by the interplay of their genotype and phenotype. There appears to be an explanatory gap between the almost perfect genetic identity and the...
Journal of Affective Disorders
August 8, 2009
Depression relapse prophylaxis with Mindfulness-Based Cognitive Therapy: replication and extension in the Swiss health care system.
Journal of Affective Disorders
July 24, 2009
Patrick Mcnamara, Sanford Auerbach, Patricia Johnson et al.
Introduction: We tested the hypothesis that REM sleep contributes to core features of cognitive dysfunction of anxious depression including negative self-appraisals, biased memory processing and unpleasant dream content. Methods: After a habituation night in a sleep lab, a convenience sample of 35 healthy college students and 20 depressed/anxious students were awakened 10 min into a REM sleep...
Journal of Affective Disorders
April 1, 2008
J.M.G. Williams, Y. Alatiq, Catherine Crane et al.
Background Bipolar disorder is highly recurrent and rates of comorbidity are high. Studies have pointed to anxiety comorbidity as one factor associated with risk of suicide attempts and poor overall outcome. This study aimed to explore the feasibility and potential benefits of a new psychological treatment (Mindfulness-based Cognitive Therapy: MBCT) for people with bipolar disorder focusing on...