TUSI Valve: Echocardiographic and Pathologic Correlates of a Novel Drug-Induced Valvular Disease-a Case Series.
CASE April 1, 2026 Juan Felipe Vasquez-Rodriguez, Gustavo Lemus-Barrios, Diego Rangel-Rivera et al.
• TUSI ("pink cocaine") use may cause serotonin-mediated drug-induced valvular disease. • Echocardiography shows reproducible thickening and restricted atrioventricular valve motion. • Histology reveals myxoid degeneration without inflammatory infiltrate. • Young patients with unexplained regurgitation require drug-use screening. • Synthetic drug use poses emerging cardiovascular risks needing...
DOI: 10.1016/j.case.2026.01.003 (opens in new tab)
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3,4-methylenedioxymethamphetamine
Echocardiography
Heart valve diseases
Tusi